is there a relationship between androgenic alopecia and benign prostatic hyperplasia?

نویسندگان

ladan dastgheib department of dermatology, molecular dermatology research center, shiraz university of medical sciences, fars, iran.

mehdi shirazi department of urology, school of medicine, shiraz university of medical sciences, fars, iran.

iman moezzi department of dermatology, molecular dermatology research center, shiraz university of medical sciences, fars, iran.

saber dehghan department of medicine, school of medicine, shiraz university of medical sciences, fars, iran.

چکیده

androgenic alopecia as a physiologic process and benign prostatic hyperplasia (bph) as a pathologic process in the older population are androgen-dependent processes influenced by 5-alpha reductase enzyme which converts testosterone to dihydrotestosterone. this cross sectional study was done to evaluate the relationship between androgenic alopecia and bph. 150 men older than 50 years old, who presented to the free prostate screening clinic, were included. they were asked about urinary symptoms. psa level, prostate volume with sonography and alopecia grading using hamilton-norwood classification (grade i to vii) were evaluated. analysis was done by spss statistical method. 59.6% of men had mild alopecia (grade i, ii, iii), 34.1% had moderate alopecia (grade iv, v) and 6.3% had severe alopecia (grade vi, vii).the mean psa level was 1.37 ± 1.48 ng/ml. the minimum psa level was 0.1 ng/ml, and the maximum level was 6.8 ng/ml. the mean prostate volume was 37.85 ± 21.85cc. the minimum prostate size was 10 ml, and the maximum volume was 173 ml. the mean international prostate symptom score (ipss) was 7.6 ± 6.11 with the minimum score 0 and the maximum score 27. however, no relationship between these parameters and androgenic alopecia was detected. this study showed that there is no relationship between androgenic alopecia, psa level, ipss, and prostate volume. occurrence of alopecia in younger age and a positive family history correlated with a higher grade of alopecia.

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عنوان ژورنال:
acta medica iranica

جلد ۵۳، شماره ۱، صفحات ۳۰-۳۲

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